Clinical value of antinuclear antibodies in rheumatoid arthritis

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Antinuclear Factor in Rheumatoid Arthritis, Its Incidence and Clinical Significance.

The antinuclear factor (ANF) test has been used in the diagnosis of systemic lupus erythematosus (SLE) for some years since it was first described in 1957 (Friou, Finch, and Detre, 1957; Holborow, Weir, and Johnson, 1957) and in this Unit it has been positive in every case of clinically active lupus erythematosus tested. ANF has also been found in the sera in some cases of rheumatoid arthritis ...

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Induction of antinuclear antibodies in patients with rheumatoid arthritis receiving treatment with human recombinant interferon gamma.

Of six patients with rheumatoid arthritis (RA) treated with human recombinant interferon gamma for two to eight months, three developed antinuclear antibodies (ANAs). This was accompanied by a simultaneous clinical exacerbation of the disease activity. In this study both anti-inflammatory and immunostimulatory effects of human recombinant interferon gamma in patients with RA were observed.

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Eosinophil-specific and other granulocyte-specific antinuclear antibodies in juvenile chronic polyarthritis and adult rheumatoid arthritis.

Sera from 151 children of whom 112 had juvenile chronic polyarthritis (JCP), and from adults with rheumatoid arthritis (RA), and from healthy pregnant females were tested for the presence of granulocyte-specific antinuclear antibodies (GS-ANA). These were detected in 20% of sera from cases of JCP, in 68% of adult RA, but in none of the controls. Eosinophil-specific ANA were the only ANA present...

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diagnostic value of anti-cyclic citrullinated peptide antibodies in patients with rheumatoid arthritis

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ژورنال

عنوان ژورنال: Immunopathology, Allergology, Infectology

سال: 2019

ISSN: 2412-320X

DOI: 10.14427/jipai.2019.2.49